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Pesquisa?? da Unicamp mostra que propriedade do maracuj� pode prevenir c�ncer de pr�stata
Frequentemente descartado, o baga�o de maracuj� � fonte de?? um extrato que pode se tornar aliado na luta contra o c�ncer. � o que indica uma tese de doutorado?? desenvolvida por meio de uma parceria entre dois
Segundo M�rio Roberto Mar�stica J�nior, professor e coorientador do estudo, a etapa pr�-cl�nica?? indicou que o composto extra�do da fruta conseguiu retardar o desenvolvimento dos tumores em experimentos feitos em camundongos, revelando ser?? um alimento com potencial de preven��o.
�Trabalhamos sempre com os alimentos no campo da preven��o, n�o da cura. N�o posso dizer?? que isso vai servir para curar a doen�a em um ano. � importante manter os p�s no ch�o e entender?? que descobrimos mecanismos que
explicam a a��o do maracuj� contra o desenvolvimento do c�ncer de pr�stata como um potencial aliado para?? a utiliza��o dele na preven��o�, destaca Mar�stica.
?? Nesta reportagem voc� vai ver:
Como foi feito o estudo?Qual � a rela��o entre?? maracuj� e c�ncer do pr�stata?Quais s�o os pr�ximos passos?
Polpa de maracuj� � 
: Pedro Santana/EPTV | {IMG} � [imgs]: Marcelo?? Costa/Marcelo Costa
professor Julian Martinez e patenteado pela universidade. Com a subst�ncia em m�os, era hora de entender a a��o biol�gica?? do composto.
�Estudamos o ponto de vista da redu��o da probabilidade de incid�ncia da doen�a, e isso foi o que a?? gente fez no modelo de c�ncer de pr�stata. Por que o c�ncer �? Porque � o mais incidente para o?? p�blico masculino e, se for descoberto logo, tem maior possibilidade de revers�o�, explica.�
O experimento utilizou
les�es na pr�stata que imitam o?? c�ncer em humanos. Os animais receberam o composto de maracuj� por cerca de 2 a 3 meses, per�odo no qual?? foi poss�vel observar a redu��o dos tumores.
Maracuj� e c�ncer de pr�stata
Mar�stica explica que o maracuj� foi escolhido por possuir compostos?? fen�licos, tamb�m conhecidos como antioxidantes. �Eles revertem, por exemplo, radicais livres. Eles impedem que esses radicais Livres se propaguem e?? que eles ajam�, explica o
papel importante no in�cio do c�ncer: quando os radicais livres est�o presentes em excesso no organismo,?? as c�lulas come�am a crescer desordenadamente e levam ao aparecimento de doen�as cr�nicas e n�o transmiss�veis, relacionadas ao estilo de?? vida.
"O estilo � um fator preponderante. Quando a gente insere um alimento ou um extrato, por exemplo, que � rico?? nesses compostos antioxidantes, ele atua para reverter esses processos que levam, em tese, ao desenvolvimento da doen�a. Ent�o, eles acabam?? sendo
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Al�m disso, a pesquisa identificou que o extrato do baga�o do maracuj� tamb�m reduziu o processo de angiog�nese -?? em outras palavras, o crescimento de novos vasos sangu�neos. �Quanto mais vascularizado for o tumor, mais ele vai crescer. Ou?? seja, tem sangue chegando ali, ent�o tem nutriente e vai crescendo. Se voc� diminui essa angiogenese, voc� diminuir� o efeito?? da subst�ncia na apoptose, ou morte das c�lulas.?
morre, s� que a c�lula cancer�gena perde essa capacidade. Esse extrato aumentou a?? porcentagem de apoptose, que � a morte dessa c�lula canc�gena�, destaca Mar�stica.
Professor M�rio Roberto Mar�sticos J�nior, da Faculdade de Engenharia?? de Alimentos da Unicamp � 
: Pedro Amatuzzi/Inova Unicamp
Quais s�o os pr�ximos passos?
O coorientador do estudo frisa que, atualmente, n�o?? h� testes em humanos em andamento, e eventuais
envolvem diversas vari�veis e quest�es �ticas.
envolv�m diversas vari�vel e quest�o �ticas,
Para o futuro,?? uma possibilidade seria o desenvolvimento de um nutrac�utico � tamb�m definido como uma categoria de suplemento alimentar feita a partir?? de alimentos que t�m compostos ben�ficos para a sa�de � � base do extrato.LEIA TAMB�M:
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valor acrescentado.�caminhar nesse dire��o do preserva��o do biodiversidade e do uso global de alimentos, para o desenvolvimento sustent�vel, do?? crescimento econ�mico e da sustentabilidade agregado, que � o nosso objetivo�.valor valor agregado
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